• Project Title: Cardiovascular Abnormalities Associated with the Emergence of Alzheimer's Disease

  • BASIS Advisor: Dr. Nancy Fisher

  • Internship Location: The George Washington University Hospital

  • Onsite Mentor: Dr. Farzad Najam

Alzheimer’s disease (AD) is a progressive brain disorder that slowly affects memory and thinking abilities in the affected individual which currently affects over five million people in the United States. As a disease of great severity, it accounts for over 70% of all cases of dementia and is predicted to affect 13 million US citizens by 2050. Working at Stoddard Baptist Global Care Nursing home for multiple years, I better understood the effects of the disease. Since there has been limited research conducted exploring the connections between the cardiovascular system and neurodegenerative disease, I intend to explore this connection further through my Senior Project. Interactions with both the research staff as well as Dr. Najam will assist in a better understanding of the role of the cardiovascular system in neurodegeneration, as well as learning about the effects of certain cardiovascular abnormalities, such as cerebral hypoperfusion and VaD, as well as the release of neurotoxins and inflammatory factors. I will also seek to explore the possibility of cardiovascular abnormalities arising from the onset of AD.