• Project Title: Cardiovascular Abnormalities Associated with the Emergence of Alzheimer's Disease

  • BASIS Advisor: Dr. Nancy Fisher

  • Internship Location: The George Washington University Hospital

  • Onsite Mentor: Dr. Farzad Najam

Alzheimer’s disease (AD) is a progressive brain disorder that slowly affects memory and thinking abilities in the affected individual, and it currently affects over five million people in the United States. As a disease of great severity, it accounts for over 70% of all cases of dementia and is predicted to affect 13 million US citizens by 2050. Working at Stoddard Baptist Global Care Nursing home for multiple years, I better understand the effects of the disease and wanted to learn more. Due to the impact of COVID-19, I was unable to work directly with Dr. Farzad Najam, the head of cardiac surgery at George Washington University Hospital, however, I was able to explore this relationship between the cardiovascular system and the onset of AD further through my own independent research. As a result, I better understand the role of the cardiovascular system in neurodegeneration, and am learning about the effects of certain cardiovascular abnormalities, such as cerebral hypoperfusion and VaD, on the emergence of Alzheimer’s disease. I also seek to explore the possibility of cardiovascular abnormalities arising from the onset of AD.